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Their results are crucial for pharmacodynamics, pharmacokinetic, and toxicological research

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In contrast, under reparative conditions, microglia may support an alternative reactive astrocyte phenotype (A2-like or neuroprotective state), associated with the secretion of anti-inflammatory mediators such as interleukin-10 (IL-10), interleukin-4 (IL-4), transforming growth factor- (TGF-), and neurotrophic factors (Zhao et al., 2024)