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Chloroquine is rarely used in the United States after multiple lawsuits in the 1960s led Winthrop Laboratories to withdraw the drugs rheumatic indications, but continues to be commonly used in Canada, Mexico, Brazil, Europe, Poland, Turkey, South Africa, and Asia [1, 2, 6, 3947]

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Effect of caffeine on the body fat and lipid metabolism of rats fed on a high-fat diet