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169 A study that included 356 male patients with coronary artery disease calculated a median (middle) testosterone-to-estradiol ratio of 15.8, and found lower testosterone-to-estradiol ratios were associated with higher levels of thromboxane B2 (a marker of blood clot risk) and lower levels of nitric oxide (a marker of vascular health)

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doi:10.1053/j.gastro.2012.09.007 [2] Buchman AL, Katz S, Fang JC, Bernstein CN, Abou-Assi SG

, Petzold, G

Numerous beneficial properties are attributed to curcumin, such as antioxidative, antiatherosclerotic, antimicrobial, immunomodulatory, and antiageing properties [58,60,62,63]