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Further studies in murine RAW264.7 cells suggest that ginsenoside Rg1 can synergize with glucocorticoids to enhance their anti-inflammatory effect (135)

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For instance, in a dopaminergic PC12 cell line, deficiencies in GSH synthesis that led to an overall decrease in cellular GSH resulted in complex I inhibition, increased indices of oxidative stress, and deficits in mitochondrial respiration, as seen in cases of Parkinsonism [15]