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10.3390/ijms21020578 37 GiordanoS.Darley-UsmarV.ZhangJ

However, the effectiveness of PDT can be limited due to local hypoxia within tumors and the presence of ROS defense mechanisms like MTH1, which can counteract the damage caused by ROS-oxidation

Atoms want to have a full outer shell so the free radicals react quickly with other substances to try attain another electron
Shelf life for properly stored lyophilized powder is 24 months

PLoS One 2011, 6 (12), e28707 10.1371/journal.pone.0028707
Cold sensitivity of TRPA1 is unveiled by the prolyl hydroxylation blockade-induced sensitization to ROS
