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het mechanisme werkt via signaleringscascades en transcriptiefactoren

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Lysosomal membrane glycoproteins bind cholesterol and contribute to lysosomal cholesterol export

doi: 10.1016/j.neuro.2006.07.018

In CRC cell lines, AGC1 KO significantly lowers aspartate and asparagine levels, decreases lactate production, reduces the NAD + /NADH ratio, and impairs the OCR [126]

Currently, there is no effective etiological treatment for DAN, and management primarily focuses on alleviating clinical symptoms and improving patients quality of life
