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High-dose COJEC reduced intracellular GSH compared to the DMSO control, whereas RSL3 led to an accumulation of intracellular GSH (Figure S4E)

Gelatin capsules have a lower tolerance to water on their interior and exterior

Consequently, ALA supplements are advisable to be consumed on an empty stomach to capitalize on the acidic stomach pH

1ah (vehicle (isotonic saline), n = 10 mice, 100 nmol kg 1 MK-801 n = 10 mice, 100 nmol kg 1 GLP-1 n = 10 mice, 100 nmol kg 1 GLP-1MK-801 n = 10 mice)

The results showed that irradiation aggravated arthritic severity, whereas ebselen treatment alleviated oxidative stress and inflammation in the synovium joints, increased collagen-II expression in the ankle joints, and finally improved the severity of arthritic clinical signs in the irradiated mice

Barbau-Piednoir, E
