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Taub, J

demonstrated that 60.6% of children with new onset diabetes were positive for autoantibodies directed towards deamidated IA-2ec compared to 19.3% positive to the wild type IA-2ec, while only 14.2% of adults with T1D and 4.1% of patients with Latent autoimmune diabetes of adults (LADA) showed autoantibodies towards deamidated IA-2 compared to 8.8% and 1.5% to the wild type IA-2ec, respectively (126)

One of the few training studies in older adults from Macaulay et al, reported increased regional CBF in the hippocampus, anterior cingulate, posterior cingulate, putamen, insula, occipital lobe, and temporal lobe following high-intensity (70%85% 1RM) RT 3 times per week for 12 weeks (Macaulay et al., 2022)

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7 , e39106 (2012)

For maintenance therapy in individuals with dietary deficiency, doses of 50150 micrograms daily are often sufficient and better tolerated