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A novel proof-of-concept study assessing the lightening effects and safety of malassezin for treatment of facial hyperpigmentation

AMPK, a key regulator of cellular energy balance (106), activation, lipogenic transcription factor suppression (107), and intestinal cholesterol absorption inhibition (108), is one of the mechanisms by which TSS has been shown to have anti-inflammatory, antioxidant, cholesterol-lowering, and anti-carcinogenic effects (109113)