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In vivo endothelial cell-specific knockout of MET (through the generation of Tie-Cre Met fl/fl mice) led to normalised vasculature, reduced intra-tumoural hypoxia, slowed glioblastoma growth and importantly, sensitised glioblastoma tumours to temozolomide treatment, prolonging mouse survival [40]

[11] Serious side effects may include anaphylaxis, and low blood potassium resulting in heart failure

What the pharmacology studies report abou

Acta Pharmaceutica Sinica B, 15 (12), 63426381

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8-12 Weeks: Long-term benefits become apparent, including enhanced tissue integrity, reduced scarring, and overall improved recovery