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phytoactive Se generally exists as selenomethionine, which is biotransformed to synthesize specific selenoproteins and is not directly toxic even at a high doses (109)

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Although the pathological hallmark of PD is the accumulation of alpha-synuclein-containing Lewy bodies, most patients also have varying degrees of other pathological accumulations, including beta-amyloid plaques and tau-tangles, which are more strongly linked with dementia onset and poor outcomes 2

Marquard J, Otter S, Welters A, Stirban A, Fischer A, Eglinger J, Herebian D, Kletke O, Klemen MS, Stoer A, Wnendt S, Piemonti L, Khler M, Ferrer J, Thorens B, Schliess F, Rupnik MS, Heise T, Berggren PO, Klcker N, Meissner T, Mayatepek E, Eberhard D, Kragl M, Lammert E (2015) Characterization of pancreatic NMDA receptors as possible drug targets for diabetes treatment

4,21 A complex interplay of genetic, environmental, and lifestyle factors influences the global distribution of breast cancer