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DNPH1, as a nucleotide sanitizer, can hydrolyze cytotoxic 5-hydroxymethyl-deoxyuridine monophosphate (hmdUMP), thereby preventing its incorporation into DNA

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This correlation is believed to be due to widespread autoimmune processes, such as destruction of thyroid follicular cells and epidermal melanocytes by cytotoxic CD8 T cells and increased levels of antithyroid peroxidase (anti-TPO) and antithyroglobulin (anti-TG) antibodies in patients with vitiligo

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Lazzerini PE, Capperucci C, Spreafico A, Capecchi PL, Niccolini S, Ferrata P, et al

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AOD9604 : AOD9604 is a synthetic peptide taken orally

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