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Valproate should not be administered to a woman of childbearing potential unless other medications have failed to provide adequate symptom control or are otherwise unacceptable
This reduction may be started at initiation of divalproex sodium therapy, or delayed by one to two weeks if there is a concern that seizures are likely to occur with a reduction

Physiology & Behavior 157 109115

Structural similarity of LPL to other human lipases suggests that the existence of a hydrophobic pore could be conserved but has not been observed due to the difficulty of studying lipase structures in the presence of an interfacial substrate
doi: 10.1016/j.bcp.2016.09.007 [DOI] [PubMed] [Google Scholar] 59
