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[58] Medical uses [edit] Treatment of deficiency [edit] Severe vitamin B 12 deficiency is initially corrected with daily intramuscular injections of 1000 g of the vitamin, followed by maintenance via monthly injections of the same amount or daily oral dosing of 1000 g

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(15) Again, significant differences, I'm sure you'll agree

This patient, a man in his forties, was critically ill and partially comatose

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Some inherited metabolic disorders (pyridoxine-dependent conditions) may require very large daily doses