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doi: 10.1016/s0014-2999(98)00618-9

A standardized Withania Somnifera Extract significantly reduces stress-related parameters in chronically stressed humans: a Double-Blind, randomized, placebo-controlled study

9,10 An algorithm for treating TNF alpha inhibitor psoriasiform eruptions has been proposed and is based on severity of skin eruption and control of the underlying disease 11 : If the skin eruption is mild and the underlying disease is controlled, continue the TNF alpha inhibitor and treat the eruption topically If the skin eruption is mild but the underlying disease is not controlled, switching within the same class is reasonable If the skin eruption is moderate to severe and the underlying disease is controlled, switching within the same class is reasonable If the skin eruption is moderate to severe and the disease is not well controlled, discontinuing TNF alpha inhibitors altogether is warranted

Mass spectrometry-based proteomic analyses were performed by the Proteomics Core Facility, Department of Immunology, University of Oslo/Oslo University Hospital, which is supported by the Core Facilities program of the South-Eastern Norway Regional Health Authority

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Then, the RAW264.7 cells were lysed using RIPA lysis buffer supplemented with 1 mM phenylmethanesulfonyl fluoride (PMSF)