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Cardiac cells constitute approximately 30%-40% of cardiomyocytes, which are essential for generating the force required for the hearts pumping function ( Figure 4 Compared with other cells, cardiomyocytes exhibit a distinct metabolic profile, relying primarily on fatty acids and glucose for energy provision

It is attributed to vitamin D stimulating the expression of the LPL gene in muscles and adipose tissue, increasing the clearance of circulating lipoprotein particles 6

Although they are understudied, a longitudinal analysis of HCoV-OC43 and 229E suggested that they constantly adapt to avoid host immunity [79]

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Such attributes of the advanced methods are vitally important for innovative studies to produce new knowledge with transformational and translational values