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Figure 2 5.1 Probiotics: strain-specific modulators of the gut-tumor-immune axis Probiotics exert their antitumor effects by reprogramming the gut microbiota to restore or enhance microbial-metabolite signaling that primes systemic and intratumoral immunity, with efficacy strictly dependent on strain specificity and tumor type

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Supporting Liver Detox Pathways In the liver, glutathione acts as a key conjugating agent in Phase II detoxification, binding to toxins, heavy metals, and metabolic waste to make them water-soluble for safe elimination

Environmental stress, changes in diet, or underlying allergies could also contribute