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Description
Recent studies demonstrated that NINJ1 deficiency failed to confer protection against ferroptotic cell death induced by RSL3 and ML162, GPX4 inhibitors, in RAW 264.7 cells and murine embryonic fibroblasts (MEFs) [33, 34]

BD, USA)

However, insulin sensitivity and glucose tolerance were maintained, likely owing to an increased conversion of saturated fatty acids (known to cause insulin resistance) to monounsaturated fatty acids mediated by stearoyl-CoA desaturase-1 (SCD1) [52]

(2014) 12:e1001833

PMID 5642099

Lichuang Cao, Qian Li, et al
