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Semaglutide 2.4 mg weekly, a novel GLP- 1 receptor agonist, was the first approved treatment for obesity

[DOI] [PMC free article] [PubMed] [Google Scholar] 84.Shimizu S., Kasai S., Yamazaki H., Tatara Y., Mimura J., Engler M.J., Tanji K., Nikaido Y., Inoue T., Suganuma H., et al

A 2019 review in Hormone and Metabolic Research documented these outcomes, while the landmark STEP 1 trial (Wilding et al., NEJM 2021) established 14.9% average weight reduction with semaglutide with direct relevance to androgen-driven conditions where adipose tissue is itself a hormonal organ

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