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The following subsections outline key smart material strategies and functional outcomes, highlighting how hybrid nanomaterials through pH-responsive systems, peptide or polysaccharide conjugation, multifunctional hydrogels, antibiotic resistance modulation, and enzyme-based nanozymes translate these dual actions into clinically relevant wound-healing solutions

In contrast, a frequency of 11% for the Y1253D mutation in another cohort of 138 oropharyngeal squamous cell carcinomas was reported (28)

A typical loading approach might use 0.75mg to 1mg daily for the first 3 to 5 days, then reduce to 0.5mg for the remainder of the protocol

Conjugation of GSH with electrophilic compounds is mainly mediated by the GSTs, a super family of Phase II detoxification enzymes classified, according to their localization and properties, into cytosolic, mitochondrial and microsomal GSTs [30]

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doi: 10.1016/0149-7634(84)90022-8