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These LNPs, co-encapsulating Cas9 mRNA and TatDE guide RNAs (gRNAs), can cleave the HIV genome within infected cells through tumor necrosis factor alpha (TNF-) stimulation, effectively preventing viral outgrowth (Herskovitz et al., 2021)
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NMDA receptor hypofunction underlies deficits in parvalbumin interneurons and social behavior in neuroligin 3 R451C knockin mice
