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126 For genes in the hypoxia response pathway, Ges group revealed that the EPAS1 rs2305389 was strongly related to HAPE risk among Han Chinese

This has led to widespread implementation of supplementation and fortification programs in staple foods across several countries (60)

Rivera-Rivas LA, Lorenzo-Benito S, Snchez-Rodrguez DB, Miranda-Ozuna JFT, Euceda-Padilla EA, Ortega-Lpez J, et al

Without enough B12, nerves lose insulation and transmit signals poorly, which leads to tingling, weakness, and in severe cases, long-term nerve damage

Ageing Res Rev 62:101115

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