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LC-MS Measurement The supernatant samples were thawed on ice and then centrifuged (10 min, 12,000 g , 4C) to separate possible precipitates from freezing

However, due to modern dietary habits and lifestyle factors, many people consider supplementation to gain its full benefits

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Additionally, recent work on overweight women reported that a low AGE diet improves insulin sensitivity [54]

Locally and throughout the body, adipocytes secrete inflammatory factors, thereby disrupting the function of their own and distant organs (53)

Compounds were identified on the basis of chromatographic properties and mass spectra by comparing with a metabolomic library of purified standards