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Stimulation of reactive oxygen, but not reactive nitrogen species, in vascular endothelial cells exposed to low levels of arsenite

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As well as GRX, GSNO, and S -glutathionylation reactions, GSTs may play important roles (Lieberherr et al., 2003

Nature 476 (7360), 293297

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This causes profound morphological changes and impairs glucose-stimulated insulin secretion by pancreatic beta cells, resulting in aberrant glycometabolic control, contributing to acute and long-term health complications 136,139,140