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Description
This is first clinical study demonstrating that a TfR antibody can deliver the enzyme IDS across the BBB into the brain for treatment of Hunter syndrome (mucopolysaccharidosis type II)

Targeting p53 therapeutically could help reduce neuronal loss in PD [34]

The enzyme protomer adopts a distorted jelly-roll fold composed of a -sheet core flanked by -helices, as previously described

DNA damaging effects, oxidative stress responses and cholinesterase activity in blood and brain of Wistar rats exposed to 9-tetrahydrocannabinol

all aged 1012 weeks) were anesthetized using isoflurane (5% induction

K.BavaS
