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This neurodegeneration is accompanied by the formation of characteristic Lewy bodies, which are intracellular inclusions composed largely of aggregated and misfolded -synuclein ( This degeneration of dopaminergic neurons is strongly linked to the generation of reactive oxygen species and oxidative stress as well as mitochondrial dysfunction, neuroinflammation, and aging (Smeyne and Smeyne, 2013)

Hepatic necrosis The rate at which functional hepatocytes are damaged is proportional to the product of the number of functional hepatocytes and the concentration of covalent binding of NAPQI

GS: glutamine synthetase

Helps Prevent Skin Cancer: One of the prominent coffee benefits for skin is its role in preventing skin cancer [4]

& Griffith, L

Pulina MV, Rizzuto R, Brini M, Carafoli E
