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While consensus does not exist regarding the exact synergistic mechanisms by which dual-agonists work, the addition of GIP agonism is posited to improve the HbA1c control and weight loss offered by GLP-1 agonists alone by enhancing insulin secretion, decreasing energy consumption, and stimulating satiety in the hypothalamus

Most patients tolerate the medication well, but those with existing heart conditions should be monitored closely

RTs Three Key Takeaways: GLP-1 Agonists Improve Asthma Control GLP-1 agonists like Ozempic and Mounjaro were linked to reduced asthma symptoms and medication use in obese patients, beyond their role in weight loss
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Spices A handful of common spices show promising effects on GLP-1 and blood sugar regulation, though most evidence comes from preclinical and cell-based studies

14, 2023 Semaglutide and Cardiovascular Outcomes in Patients Without Diabetes A Michael Lincoff, et
