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Glutathione biosynthesis occurs exclusively in the cytosol through a two-step ATP-dependent process

Folate is naturally present in many foods, including vegetables (especially dark green leafy vegetables), fruits and fruit juices, nuts, beans, peas, seafood, eggs, dairy products, meat, poultry, and cereals [290]

doi: 10.1177/1352458511421055 62 Iridoy ZuletMPulido FontesLAyuso BlancoTLacruz BescosFMendioroz IriarteM

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10.1016/S0024-3205(99)00241-6 52 MollazadehH.CiceroA

Moreover, they figured out that heme oxygenase-1 (HMOX1) was the major culprit for iron release in DOX-induced cardiotoxicity and provided intriguing insights for the first time into the role of ferroptosis in cardiac cell death linked to cardiomyopathy [19, 106]