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Gastroenterology 137 , 466481 (2009)

The infantile presenting complex I disorders include Leigh syndrome, fatal infantile lactic acidosis (FILA), neonatal cardiomyopathy, leukoencephalopathy, pure myopathy, and combined hepatopathy and tubulopathy
IUBMB Life 64: 362369, 2012 [DOI] [PMC free article] [PubMed] [Google Scholar] 102.Stanton RC, Seifter JL, Boxer DC, Zimmerman E, Cantley LC

Vitamin B12 plays a role in supporting mental and cognitive performance
Excessive ROS not only causes direct neuronal damage, but also potentiates microglial activation and pro-inflammatory cytokine release, thereby sustaining a neuroinflammatory environment and exacerbating neurodegeneration [63]

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