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Direct antioxidants are small molecules that possess redox-active properties, capable of scavenging ROS or reactive nitrogen species

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Bustillo JR, Rowland LM, Mullins P, Jung R, Chen H, Qualls C, et al

First described by the Italian chemist Michele Peyrone as early as in 1845, cis -diamminedichloroplatinum(II) (CDDP, best known as cisplatin or cisplatinum), is the founding member of a class of antineoplastic agents born in the second half of the 19th century around the peculiar atomic configuration of platinum

Glutathione is an antioxidant naturally occurring in the body and protects cells from damage caused by free radicals and toxins