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These images indirectly suggest the initial overexpression of Nrf2-generated GSH as stimulated by reactive oxygen and reactive nitrogen species (60)

The tradeoff for the longer timeline is better durability and muscle preservation

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1 Introduction Globally, knee osteoarthritis (KOA) is one of the most commonly occurring disabling conditions, affecting over 364 million adults (Li et al., 2024), and it is widely recognized as the most prevalent and representative form of osteoarthritis (OA)

SOD provides a frontline of defense against ROS by inhibiting O2 [45]