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A study attempting to identify the prevalence of LAL-D from patients with abnormal results in laboratory databases (elevated LDL-C and abnormalities on liver tests) identified a total of 1825 patients who subsequently underwent a dried blood spot sample for determination of LAL enzyme activity

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CMAJ (2014) 186:E295

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When comparing the 1.5 g doses of carnitine and acetylcarnitine, the acetylcarnitine AUC showed a 3fold decrease

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This may be partially due to differences in access to food and medical care or the higher rates of osteoporosis in women (34)

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