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Muller AP, Fernandez AM, Haas C, Zimmer E, Portela LV, Torres-Aleman I (2012) Reduced brain insulin-like growth factor I function during aging

However, most of the previous studies have been based on in vitro experiments or correlational studies, with a lack of large-sample clinical studies

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Anti-inflammatory effects of isoalantolactone on LPS-stimulated BV2 microglia cells through activating GSK-3-Nrf2 signaling pathway

Long, Zeng, Shi, Tian, and Chen at West China Hospital of Sichuan University published a systematic review and meta-analysis in Free Radical Research in 2014, pooling data from 35 prospective studies involving 571,511 participants and 72,196 deaths