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They found that miR-34a-overexpressing mice showed significantly reduced tumors as compared to EV-injected mice suggesting that miR-34a functioned as a tumor suppressor in vivo

Inhibition of HMGB1 release via salvianolic acid B-mediated SIRT1 up-regulation protects rats against non-alcoholic fatty liver disease

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The median age in these cohorts is about 55 years in the D and DG groups