klowa art café (@klowa_artcafe) · Lytton, BC A Cup of Art: Tribe

Inhibition of GSH and Trx metabolism with buthionine sulfoximine (BSO) and auranofin (AUR), respectively, induced significant decreases in clonogenic survival compared to either drug alone in FaDu, Cal-27 and SCC-25 HNSCC cells in vitro and in vivo in Cal-27 xenografts

For detailed information on the importance of glutathione and causes of deficiency see our blog What is Glutathione and Why Do We Need It

The rs1050450 (Pro198Leu) polymorphism of glutathione peroxidase 1 (GPx1), a selenium-dependent antioxidant enzyme, may modulate selenium status and enzymatic activity

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