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Whether thrombin-induced, fibrin-mediated pathways also act on synaptic transmission and plasticity, and the role of PAR1 in this context has not been addressed so far
10.1073/pnas.2103592118 195 WongC
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Lscher W, Potschka H, Sisodiya SM et al (2020) Drug resistance in epilepsy: clinical impact, potential mechanisms, and new innovative treatment options
Serpina3n limits cartilage destruction in osteoarthritis by inhibiting macrophage-derived leucocyte elastase
As such, HDL-Cs causality in protection from CVD is difficult to define and is somewhat controversial, mainly due to epidemiological discrepancies between the dose-response of HDL-C levels to CVD outcomes
