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All three boxes share three common features: a glutamine residue, hydrophobic pockets, and positively charged residues that mediate interactions with the peptides

Arch Intern Med 140(11):14731475 Ruginsk SG, Lopes da Silva A, Ventura RR, Elias LLK, Antunes-Rodrigues J (2009) Central actions of glucocorticoids in the control of body fluid homeostasis: review

The tail vein injection represents the most widely used systemic approach, offering advantages such as ease of operation and feasibility for repeated dosing

These findings validate the therapeutic targeting of the system Xc pathway, although challenges related to tumor selectivity and potential systemic toxicity remain

Inducible NOS, iNOS The major functions of NO production through activation of iNOS are associated with the bactericidal and tumoricidal actions of macrophages