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6.3 Translational platforms for therapeutic innovation Organoid-based drug screening: Develop patient-derived intestinal organoids co-cultured with personalized gut microbiota to test radioprotective compounds (e.g., NRF2 agonists, exosome-based therapies) and identify responders/non-responders

Though weight loss injections are not a quick route to fitness, they can provide a strong kick-startparticularly for clients who have stalled or found traditional methods challenging

On Monday, the Food and Drug Administration approved baricitinib, a once-a-day pill developed by the drugmaker Eli Lilly to treat alopecia areata, an autoimmune disease that triggers sudden hair loss

To measure ROS production, 10 M Amplex UltraRed, 1 U/mL horseradish peroxidase (HRP), and 5 U/mL superoxide dismutase (SOD) were added to the chamber

Briefly, 10.000 cells per well were seeded in a 96-well plate

doi: 10.1038/s41467-019-09277-9 39 CardonaCJMontgomeryMR