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Consequently, an attempt was made to emulate that effect in patients with cirrhosis and HE in a pilot study, and GPB was shown to be capable of reducing NH3 levels in those patients.50 A later study by Rockey et al

Eslicarbazepine: Higher affinity for the inactive state of the voltage-sensitive sodium channel (causing greater inhibitory effect on rapidly firing neurons

doi: 10.1016/j.chroma.2009.06.038

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Clinical and pathophysiological characteristics of cirrhotic patients with grade 1 and minimal hepatic encephalopathy