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In the APP/PS1 transgenic amyloidosis mouse model, 0.5 g daily IN-NAP for 3 or 6 months reduced A 40 and A 42 isoforms and hyperphosphorylated and insoluble tau, and also improved cognitive performance in the Morris water maze [103,104]
Liu J, Ren ZH, Qiang H, Wu J, Shen M, Zhang L, Lyu J
Accordingly, the bottom line in an acetaminophen overdose is that when the amount of NAPQI is too much for the available glutathione to detoxify, liver damage occurs
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doi: 10.1080/10406630008028530
