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doi:10.1016/S0140-6736(69)91856-X

Authors inferred that androgen determined penile development in specific masculinisation programming window (MPW) while subnormal androgen could not be reversed by later supplement 17,19

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Dosing or placement errors: Excess units or injections placed too low/high can affect unintended muscle groups, leading to strain or botox and neck pain

This is not a formal ceiling because no FDA-approved limit exists, but it represents the upper range of what is supported by preclinical scaling and provider experience
