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While the etiology of NTD is multifactorial, some studies have found that blood concentrations of homocysteine or holo-transcobalamin to be lower in NTD-affected infants and mothers compared to non-affected controls (reviewed in 59)

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Fc-receptors as regulators of immunity

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However, to fully realize the therapeutic potential of the ENS, ongoing clinical trials, long-term follow-up studies, and interdisciplinary collaboration are necessary to address the remaining scientific and clinical challenges

M-mode measurements of the LV cavity size in systole and diastole were made, and global LV function was assessed by calculating ejection fraction (EF) from end-diastolic and end-systolic volumes of the left ventricle according to the following equations: diastolic volume (DV) (mL) = 0.001047 left ventricle internal dimension in diastole (LVIDd (mm)) (Balenovic et al., 2009)