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doi: 10.1016/j.redox.2014.01.002

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The virus infected animals were intranasally inoculated with 0.1 mL PBS containing 10 5 PFU SARS-CoV-2

To overcome this limitation, near-infrared emitting agents for deep tissue penetration are required
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2.1.2 Activation of antioxidant enzymes Studies in rodent models have shown that molecular hydrogen activates the Nrf2 transcription factor, which induces expression of several endogenous antioxidant enzymes [24]