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Following treatment with 5-aza-dC, the expression levels of nuclear genes ( CFH , EFEMP1 , VEGFA , and NFkB2 ) in both H and J cybrids became comparable, indicating that mtDNA variants may modulate AMD progression through their effects on DNA methylation
[DOI] [PMC free article] [PubMed] [Google Scholar] 20.Wang J., Huang P., Yu Q., Lu J., Liu P., Yang Y., Feng Z., Cai J., Yang G., Yuan H., et al

Control checklist: vehicle, BPC 157, TB 500, blend

The highest mRNA transcript level (63-fold) is recorded at 16 hours of UV-B exposure

& Edwards, J
2014;9 doi: 10.1371/journal.pone.0113650
