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Dysregulation of GSH synthesis is increasingly being recognized as contributing to the pathogenesis of many pathological conditions

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For mushroom mycelium, hot water extractionfor example, subjecting mycelial suspensions to a 100 C water bath for 5 minhas been shown to efficiently leach EGT into an aqueous solution [36]

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Another large study investigating the impact of KD on AD patients noted increased irritability and fatigue, but no other serious side effects were reported [208]