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Despite the tendency towards apoptosis, Ito et al

In a recent study of outpatients with ILDs, including IPF, depression score, functional status (as assessed by walk test), as well as pulmonary function, all contributed to the severity of dyspnea

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Advancing this field will require a biomarker-guided approach, incorporating metrics such as NRF2 activity ([ 18 F]FSPG PET), peroxiporin expression, GPX4-SLC7A11 status, iron levels (T2*MRI), and tissue oxygenation (OE-MRI/[ 18 F]FMISO-PET) to tailor context-specific dosing and therapeutic combinations, thereby accelerating clinical translation

3D migration assays Primary FRCs were isolated from C57BL/6J or B6 Cd44 / spleens and cultured as described 55

Beyond GABA, DSIP influences several other neurotransmitter systems