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The refined subtrees were midpoint-rooted using FastRoot [58], and tips were initially clustered using TreeCluster v1.0.4 (branch length threshold = 0.02, single linkage) [59]

Peer review Peer review information Nature Chemical Biology thanks Sheng-Cai Lin, Zhimin Lu and the other, anonymous reviewer(s) for their contribution to the peer review of this work

Supernatant was used for immunoblotting with the indicated antibodies

Multiple antioxidant therapeutic strategies are being investigated because of the importance of OS in the pathophysiology of IBD to eliminate ROS, enhance AOE activities, and inhibit abnormal redox signaling ( Figure 2 )

Pure Bio Labs BPC-157 + TB500 is a high-purity peptide offered in a 5mg/5mg lyophilized powder format, intended strictly for laboratory research and development purposes

Lipid peroxidation, GSH depletion, and SLC7A11 inhibition are common causes of EMT and ferroptosis in A549 cells, but different in specific mechanisms