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Enhance Metabolism: B12 plays a role in metabolizing fats and proteins, which can aid in maintaining a healthy metabolism

Acknowledgements This research was supported by the National Key R&D Program of China (2024YFA1212500), the National Natural Science Foundation of China projects (32171320 and 82302384), the Key Project of the Natural Science Foundation of Shaanxi Province (2025JC-QYCX-066), the National University of Singapore (NUHSRO/2020/133/Startup/08, NUHSRO/2023/008/NUSMed/TCE/LOA, NUHSRO/2021/034/TRP/09/Nanomedicine, 23-0173-A0001), the National Medical Research Council (MOH-001388-00, CG21APR1005, OFIRG23jul-0047), the National Research Foundation (NRF-000352-00), and start-up funding from Shandong Cancer Hospital (rcyj-202603) Ethics declarations Competing interests The authors declare no competing interests

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This evidence supports the notion that single herbs can serve as effective adjuncts in the holistic treatment of PCOS, emphasizing the importance of individualized herbal therapy based on specific patient needs

Apoptosis and autophagy have been proven as major forms of PCD and play important roles in the treatment of UC

As evidence for the possibility of an early life disturbance creating lasting effects on barrier function, the trauma of maternal separation during weaning has been shown to predispose adult rats to enhanced intestinal permeability in response to stress [51]