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In vitro and in vivo studies of the last years, as well as our own therapy experiences show a significant antiproliferative and pro-apoptotic effect in tumors by means of: Figure 3

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In RBCs pre-incubated with the anthocyanin extract and then treated with 50 mM AAPH, the rate constant (0.048 0.001 min 1 ) was not different than that of RBCs treated with 50 mM AAPH alone and was significantly different with respect to control (Table 3)
In contrast, knock down of Nrf2 suppresses tumor growth, inhibits cell proliferation and promotes increased apoptosis [44, 49]

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