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Role of mitochondrial dysfunction in neurotoxicity of MPP+: Partial protection of PC12 cells by acetyl-L-carnitine

Factors like age and stress may also lower the bodys regular production of CoQ10. In fact, most people start to produce less CoQ10 starting at the age of 21. Why does that matter? This coenzyme is a powerful antioxidant that helps protect the body from free radicals that can damage otherwise healthy cells. Because cells are the building blocks of every part of your body, healthy cells are a necessity

On another hand, shikonin a polyphenol widely used in Chinese traditional medicine has shown to suppress glucose consumption and lactate production as well as inhibit the nuclear translocation and enzymatic activity of PKM2, which is responsible for stimulating the Warburg effect in macrophages, in a DSS-induced colitis mouse model (222)
Interaction between gut microbiota and the sympathetic nervous system in blood pressure regulation

Eur J Nutr 55(1):5561

M., Daniewski, A
